Edited by AERĪll of those mods are compatible with CCO, you need to add in the modified esps from the CCO site for those mods. As far as I can tell, there is no patch for 101Bugs + Requiem, unfortunately. I don't want to uninstall it now due to possible savegame issues, and I would rather not start over yet. I've decided to just ignore this for now, but I wish I had known prior to starting, and I would have uninstalled 101Bugs then.
The crafting components added by 101Bugs don't work correctly with Requiem. Plus, RND doesn't recognize seawater in certain types of bottles. I had to install the Real Water Two patch to make it work, and the 'Drink from Stream' hotkey still isn't behaving as it should all of the time. Realistic Needs and Diseases has had a couple of minor issues. It's pretty rare, so I'm just going to ignore it. This includes, for example, the carriage drivers.
Sometimes, some of the NPCs are naked (well, in their undergarments only). Frostfall and Cloaks of Skyrim worked fine, but for some reason the Winter is Coming patch screwed up the hair on most of the NPCs (I have no idea why). I downloaded the patches for each of the three.
I realized that Frostfall, Winter is Coming, and Cloaks of Skyrim were not Complete Crafting Overhaul-compatible. I added ETaC, Inns and Taverns, and Better Fast Travel to my list after installing SSME, and I've been playing through without any major crashes or difficulties so far.